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Loss of the tumor suppressor LKB1 promotes metabolic reprogramming of cancer cells via HIF-1alpha

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When gene-modified mice were used, age-, sex-, and strain-matched WT mice were chosen as controls

Interestingly, a putative gene for glutamine synthetase (GS) is retained despite glutamine being an abundant amino acid in human and mosquito hosts

*Correspondence: Ming You, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers